Med Plant Data Base

Order
Family

Moldo-german project 10.820.09.09GA
«Evaluation of the pharmaceutic potential
of medicinal plants from natural habitats from Republic of Moldova
»

advanced

Polygonatum multiflorum

KINGDOM: Plantae » Class: Liliopsida » Order: Asparagales » Family: Asparagaceae

Polygonatum multiflorum

Species


Polygonatum multiflorum

Taxonomy


Kingdom: Plantae

Class: Liliopsida

Order: Asparagales

Family: Asparagaceae

Genus: Polygonatum

Species: multiflorum

Plant description


It is in flower in June, and the
seeds ripen in October. The flowers are hermaphrodite (have both male and
female organs) and are pollinated by Bees. The plant is self-fertile.

The plant prefers light (sandy), medium (loamy) and heavy (clay) soils,
requires well-drained soil and can grow in heavy clay soil. The plant prefers
acid, neutral and basic (alkaline) soils. It can grow in full shade (deep
woodland) or semi-shade (light woodland). It requires dry or moist soil and
can tolerate drought.

Diffusion area


He Shou Wu is a very famous herb
in the Orient, used by millions regularly to help develop Qi. It is China's
most renowned "longevity herb." It has acquired a broad reputation
as a youth preserver, rejuvenator and sexual tonic.The Chinese common name for fo-ti,
he-shou-wu, was the name of a Tang dynasty man whose infertility was
supposedly cured by fo-ti; in addition, his long life was attributed to the
tonic properties of this herb. Since then, traditional Chinese medicine has
used fo-ti to treat premature aging, weakness, vaginal discharges, numerous
infectious diseases, angina pectoris, and impotence.


Ecology


In shaddy forests, more rarely
on deforested lands. Grows solitarily. Is widespread.

Therapeutic actions


Solomon's seal has been used for
thousands of years in herbal medicine. It is used mainly in the form of a
poultice and is believed to prevent excessive bruising and to stimulate
tissue repair. The root is astringent, demulcent, emetic and tonic. An infusion
is healing and restorative, it is good in the treatment of stomach
inflammations, chronic dysentery etc. It is used with other herbs in the
treatment of pulmonary problems, including tuberculosis, and women's
complaints. The powdered roots make an excellent poultice for bruises, piles,
inflammation etc. The root is harvested in the autumn and dried for later
use. The plant should not be used internally except under professional
supervision. A distilled water made from the whole plant has been used as a
skin tonic and is an ingredient of expensive cosmetics. The dried powdered
roots and flowers have been used as a snuff to promote sneezing and thus
clear the bronchial passages.

Also, It is used mainly in the form of a poultice and is believed to
prevent excessive bruising and to stimulate tissue repair. The root is
astringent, demulcent, emetic and tonic. An infusion is healing and
restorative, it is good in the treatment of stomach inflammations, chronic
dysentery etc. It is used with other herbs in the treatment of pulmonary
problems, including tuberculosis, and women's complaints. The powdered roots
make an excellent poultice for bruises, piles, inflammation etc. The root is
harvested in the autumn and dried for later use.


Biologically active substances



The active constituents of fo-ti
have yet to be determined. The whole root has been shown to lower cholesterol
levels, according to animal and human research, as well as to decrease
hardening of the arteries, or atherosclerosis. Other fo-ti research has investigated
this herb's role in strong immune function, red blood cell formation, and
antibacterial action. The unprocessed roots possess a mild laxative effect.

 Chemical studies of he shou wu have revealed
the presence of chrysophanol and emodin (both in the free state and combined
as glycosides) together with a small amount of rhein. All of these
anthraquinone derivatives possess cathartic properties that account for the
drug's noted effectiveness in the treatment of constipation. In Chinese
literature, a distinction is made between "raw he shou wu" and
"cured he shou wu." The latter undergoes steaming for twelve hours
and sun drying for eight hours, with the processes repeated up to nine times.
Recent Chinese works call for steaming for thirty-two hours, which results in
a reduction of free and conjugated anthraquiones by 42 to 96 percent. Most
Western literature on the drug fails to distinguish between the processed and
unprocessed root. More recent Chinese studies have also shown antimicrobial,
liver protectant, and cholesterol-reducing activity.

 Constituents:
chrysophanol(C15H10O4),emodin(C15H10O5),0.00735%,rhein(C15H8O6),0.00089%,lecithin(3.7%);
2,3,5,4'-tetrahydroxystilene-2-O-beta-D-glucoside, C20H22O9, 1.2%.

 Phospholipid (lecithin, 3.7%);
Chrysophanol; Emodin; Physcion; Emodin-1-6-dimethylether; Questin; Emodin-citrosein;
Questinol; 2-acetylemodin; Chein; Chrysophanol anthrone; Rhapontin;
Emodin-8-I-a-D-glucoside; 2-methoxy-6-acetyl-7-methyjuglone; Tricin;
N-transferuloyltyramine; N-transferuloyl-3-methyldopamine; 2, 3, 5,
4'-tetrahydroxystilbene-2-I-a-D-glucoside.



 Main Constituents of Foti Root:
 Chrysophanol,C15H10O4;Emodin,C15H10O5,0.00735%;Rhein,C15H8O6,0.00089%;Lecithin,3.7%;2,3,5,4'-tetrahydroxystilene-2-O-beta-D-glucoside,C20H22O9,1.2%.

 Other Phytochemicals:

 Chrysophanolanthrone;physcion;emodin1,6-dimethylether;questin;citreotosein;questinol;2-acetylemodin;physcion-8-O-beta-D-glucoside;2-mithoxy-6-acetyl-7-meth-yiuglon;2,3,5,4'tetrahydroxystilbene-2-O-beta-D-glucoside,1.2%;2"-O-monlagalloylesters
2,3,5,4'-tetrahydroxystilbene-2-D-glucopyranoside;3"-O-monogalloylesters
2,3,5,4'-tetrahydroxystilbene-2-O-D-glucopyranoside;2,3,5,4'tetrahydroxystilbene-2-O-(6"-O-alpha-D-glucopyranosyl)-Beta-D-glucopyranoside;polygonimitin
B;beta-sitosterol;2,3,4,6-tetrahydroxyacetophenone-3-O-beta-D-glucoside;quercetin-3-O-galactoside;quercetin-3-O-arabinoside;resveratrol;phosphatidyl
ethanolamine;phosphatidic acid;phosphatidyl glycerol;diphosphatidyl
glyeerol;protine;serine;glutamate;theronine;arginine;alanine;valine;tricin;N-transferuloyl
tyramine;N-trans-feruloyl-3-methyldopamine;daucosterol;gallic
acid;catechin;epicatechin;3-O-galloyl-catechin;3-O-galloyl-proyamidin
B;3,3'-D-O-galloyl procyanidin B2;1-O-stearoyl-2-O-delta4',7'-dode
cenoyl-3-O-phosphatidic
acid-O-beta-D-glucoside;1-O-stearoyl-2-O-delta4',7'-dode cenoyl-3-O-phosphatidic
acid-O-(6"-O-alpha-D-glucose)-beta-D-glucoside,etc.

 Constituents of Extract:

 An alcoholic extract from fo-ti
roots yielded three bioactive compounds: E-2,3,5,4'-tetrahydroxystilbene,
2-O-beta-D-glucopyranoside(2,3,5,4'-tetrahydroxystilbene 2-O-glucopyranoside)
and cis- and
trans-E-3-butylidene-4,5,6,7-tetrahydro-6,7-dihydroxy-1(3H)-isobenzofuranone.
Two of these compounds were found to be calcium-ATPase inhibitors.

Indigenous medicinal plants in databases


Coada soricelului – Achillea

millefolium L.

Corn – Cornus mas L.

Cosaci – Astragalus dasyanthus

Pall.

Cretusca – Filipendula ulmaria L

Crusin – Frangula alnus Mill.

Cucurbetica – Aristolochia

clematidis L.

Centers, institutes, research labs of medicinal plants


http://www.plantarium.ru/page/search.html

http://www.agroatlas.ru/ru/content/weeds/Persicaria_lapathifolia/map/

http://www.lunevan.narod.ru/persicaria_lapathifolia.html

http://www.binoz.uj.edu.pl:8080/chromosomes/pages/main.jsf

References


http://server9.web-mania.com/users/pfafardea/database/plants.php?Polygonatum+multiflorum

http://www.binoz.uj.edu.pl:8080/chromosomes/pages/main.jsf


Genetic characteristics


2n = 18

Gathering place (figure should be increased)



Polygonatum multiflorum
DLE íîâèíêè

Copyright © Universitatea Academiei de Stiinte a Moldovei
Copyright © Gincota Filipp