Med Plant Data Base


Moldo-german project 10.820.09.09GA
Evaluation of the pharmaceutic potential
of medicinal plants from natural habitats from Republic of Moldova


Aristolochia clematitis

KINGDOM: Plantae » Class: Magnoliopsida » Order: Aristolochiales » Family: Aristolochiaceae

Aristolochia clematitis


Aristolochia clematitis


Kingdom: Plantae

Class: Magnoliopsida
Order: Aristolochiales

Family: Aristolochiaceae

Genus: Aristolochia

Species: A. clematitis

Plant description

Aristolochia is a genus of
evergreen and deciduous woody vines and herbaceous perennials. The smooth
stem is erect or somewhat twining. The simple leaves are alternate and
cordate, membranous, growing on leaf stalks. There are no stipules.

The flowers grow in the leaf axils. They are inflated and globose at the
base, continuing as a long perianth tube, ending in a tongue-shaped, brightly
colored lobe. There is no corolla. The calyx is one to three whorled, and
three to six toothed. The sepals are united (gamosepalous). There are six to
40 stamens in one whorl. They are united with the style, forming a
gynostemium. The ovary is inferior and is four to six locular.

These flowers have a specialized pollination mechanism. The plants are
aromatic and their strong scent attracts insects. The inner part of the
perianth tube is covered with hairs, acting as a fly-trap. These hairs then
wither to release the fly, covered with pollen.

The fruit is dehiscent capsule with many endospermic seeds.

The common names "Dutchman's Pipe" and "Pipevine" (e.g.
Common Pipevine, A. durior) are an allusion to old-fashioned meerschaum pipes
at one time common in the Netherlands and Northern Germany.
"Birthwort" (e.g. European Birthwort, A. clematitis) refers to
these species' flower shape, resembling a birth canal. Some reference
books state that the scientific name Aristolochia was
developed from Ancient Greek aristos

Diffusion area

Grows in Southern Europe and
South America.


Is found in the valleys of
forest, flooded grasslands, in ravines, on the banks of rivers and seas, as a
weed - in gardens and orchards.

Therapeutic actions

It was formerly used as a
medicinal plant (though poisonous) and is now occasionally found established
outside of its native range as a relic of cultivation. A recent study
suggests that it is the cause for thousands of kidney failures in Romania,
Bulgaria, Serbia and Croatia where the plant is unintentionally consumed
through flour. This has been discovered after a clinic for obesity in Belgium
used Aristolochiaceae as a diuretic, after a few months some of the subjects
suffered from kidney carcinoma and kidney failure.

The presence of Aristolochic acid, isolated from the subterranean parts of
the plant, must be emphasized here. It is toxic and an irritant, as well as a
stimulant of phagocytosis. It is a yellow, bitter substance with a phenathrenic
nucleus, and it comprises a nitrate group. Historical dose: Trituration and
all potencies, 3x to 30c. Aristolochia Clematitis have Aristolochic acid,
isolated from the subterranean parts of the plant, must be emphasized here.
It is toxic and an irritant, as well as a stimulant of phagocytosis. It is a
yellow, bitter substance with a phenathrenic nucleus, and it comprises a
nitrate group. Historical dose: Trituration and all potencies, 3x to 30c.
Planets: Moon, Venus.

Herbal - Aristolochia Clematitis, of the Aristolochiaceae family, grows in
Southern Europe and South America. Its active principle is clematine, which
is identical to the Aristolochia or the Serpentarin as well as to
non-purified Aristolochic acid. Aristolochic acid causes menorrhagia, tends
towards miscarriage, and has a toxic action on the kidneys and liver
parenchyma as well as intestinal mucous membranes.

Aristos means better, locheia means giving birth. In popular medicine to
induce birth or stimulant the menses. Also as a diuretic, and against
rheumatism. In high doses it is an emetic and cathartic. In South America,
some Aristolochia are used for blindness.

The proving by Mezger made use of the Spring rhizome. The experiment was
carried out by eighteen provers, of whom thirteen were women. The following
potencies were studied: 5x, 2x, 12x and mother tincture. The experiment
lasted for twelve weeks.

HOMEOPATHIC -- Excess of estrogen hormones produced. Marked affect on the
urinary passages, kidneys, venous system, skin. Menses irregular.
Pre-menstrual insomnia with agitation and congestion of the pelvis. Joint
pains improved by movement. State of fatigue, or the opposite. Worn out with
vertigo, chilliness, slightly improved by heat. Hunger pangs and need to eat
despite feeling nausea. Tendency to plumpness.

CLINICAL - After-pains. Amenorrhea. Anorexia. Arthritis. Bedwetting.
Bronchitis. Chills. Colic. Cystic mastitis. Cystitis. Depression.
Dysmenorrhea. Eczema. Enteritis. Hormonal imbalances. Insomnia. Laryngitis.
Mastitis. Menopause. Metritis. Nephritis. Pre-menstrual syndrome. Rheumatism.
Spasmodic colitis. Sinusitis. Vaginitis. Varicose veins. Vertigo.

Constitutions - Hormonal imbalances. Subjects of a nervous constitution,
with extreme sensitivity, and who cry easily. Tubercular conditions of the
worn-out type.

Modalities - Better during menses. Better from elimination of secretion and
worse from suppression. Worse before and after menses.

MIND - Sensation of solitude. Fear for the future. Rejects company.
Psychosomatic complaints tending towards depression, especially in women who
are going through the menopause (Sep.). State of mental depression.
Amelioration of depressed state by fresh air and menses. Mental condition
aggravated before and after periods, clearly ameliorated during menstrual

Abdomen - Colic. Spasmodic colitis. Enteritis. Abdomen distended, painful,
before and during menses.

Breasts - Pain and feeling of hardening of the left breast. Pain in the
breast. Cystic mastitis.

Chest - Chest feels hard, like a breast-plate.

Eyes - Watering aggravated by light, reading. Burning and itching.

Female - Brown discharge, watery flow. Eczema of the vulva. Sensual itching,
aggravated before menses, ameliorated during menses, aggravated after menses.
Menses absent, late or short, Blood black, with clotting. Varicocele.
Amenorrhea. Dysmenorrhea. Infrequent menses. Metritis. After-pains with
laryngitis. Vaginitis.

Food - Anorexia, nausea with vertigo and cold sensations.

Head - Diffuse headaches, improved in the fresh air and by cold, damp
compresses. Congestive headache (Bell.).

Kidneys - Pain in the kidneys and bladder with a frequent urination.
Bedwetting, especially in older women. Incontinence and compelling need to
urinate. Pyelitis. Cystitis. Albuminuria with white discharge.

Limbs - Arthritis in women with the menopause. Rheumatism of the knee.
Limbs cold, with chilblains, skin discolored or red. Legs heavy before
menses. Joint pains improved by movement, aggravated in the sitting position.
Fingers and toes swollen before menses. Swollen, distended varicosities
before menses. Varicose veins.

Lungs - Bronchitis. Angina, laryngitis with hoarseness. Morning cough,
thorax painful on left side.

Mouth - Mouth painful, with cracked corners of the lips. Teeth painful,
aggravated by cold food, and ameliorated by hot food.

Nose - Sinusitis. Coryza in the morning, improved by getting up, by fresh
air. Watery flow, improved between 8 a.m. and 9 a.m.

Rectum - Rectum prolapsed after eating. Rectal weakness. Mucus diarrhea,
hemorrhoid bleeding between stools, which contain mucus.

Skin - Varicose eczema. Acrocyanosis in young girls. Burns, also for
external use in compresses of liquid extract at 15%, diluted 1:50 in

Stomach - Acrid dyspepsia.

Biologically active substances

Aristolochia acids, tannins,
phenolic acids (ferulic and caffeic acid), cetyl alcohol and

Volatile oil contain borneol, and ionolul.

Roots with acids containing allantoin, alkaloids: magnoflorină,
taliscanină, chakranină, sesquiterpenoid lactones:
aristrolactonă and polyphenolcarboxylic acids.

Indigenous medicinal plants in databases

Brusture Arctium lappa L.

CastanAesculus hippocastanum L

Calin Viburnum opulus L.

Catina Hippophae rhamnoides L.

Cerentel Geum urbanum L.

Cicoare Cichorium intybus L.

Cimbrisor Thymus serpyllum L

Cimbru Thymus vulgaris L.

Ciubotica cucului Primula veris L.

Coacaz Ribes nigrum L.

Coada calului Equisetum

arvense L

Coada soricelului Achillea

millefolium L.

Centers, institutes, research labs of medicinal plants


Dicționar dendrofloricol,
Editura științifică și enciclopedică,
București, 1989;

Botanică farmaceutică, Editura didactică și
pedagogică, București, 1981;

Medicină naturistă, Editura medicală, București,

Pârvu C. Universul plantelor. Mica enciclopedie. Editura
enciclopedică. Bucureşti 2000. p.442. (Aristolochia clematitis p.

Genetic characteristics

2n = 14

Gathering place (figure should be increased)

Aristolochia clematitis

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